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DTSTAMP:20250910T043017Z
DESCRIPTION:The Killam Seminar Series presents Deep brain stimulation: new 
 targets\, new techniques\, new indications.\n\nThe seminar will be taking 
 placed in person at The Neuro (Jeanne Timmins Ampitheatre)\n\nTo attend in
  person\, register here\n\nTo attend virtually\, register here.\n\nSpeaker
 : Pepijn van den Munckhof\, PhD\n\nDepartment of Neurosurgery\, Amsterdam 
 University Medical Center\, Amsterdam\, The Netherlands\n\nAbstract: Since
  the introduction of permanently implantable deep brain stimulation (DBS) 
 systems in the 1980s\, hundreds of thousands of patients throughout the wo
 rld have undergone DBS surgery. In the beginning the majority were patient
 s with Parkinson’s disease or tremor undergoing DBS of the thalamus\, but 
 DBS is currently applied in many different diseases. Also\, the preferred 
 brain target for many indications evolved over the years due to improved b
 rain imaging techniques. During my medicine study\, PhD and neurosurgical 
 residency I became fascinated by basal ganglia functioning and DBS. My res
 earch interests focus on improving the outcome of DBS surgery in establish
 ed indications and the application of experimental DBS in new indications.
  In the Killam Seminar\, I will overview several DBS developments in the f
 ield of obsessive-compulsive disorder\, Parkinson’s disease\, and disorder
 s of consciousness & arousal.\n\nBio: Pepijn van den Munckhof (born in 197
 3 in Nijmegen\, the Netherlands) studied Medicine at the University of Gro
 ningen from 1991-1999. In 1996-1997\, he spent a research year with Leo Ve
 rhagen Metman and Thomas Chase at the Experimental Therapeutics Branch of 
 the National Institute of Neurological Diseases and Stroke (NIH\, Bethesda
 \, USA)\, studying levodopa response fluctuations in Parkinson’s disease. 
 From 1999-2002\, he went to Montreal for a Master’s in Molecular Biology a
 t the Université de Montréal. During these years\, he studied basal gangli
 a development in the naturally occurring aphakia mouse model of Parkinson’
 s disease in the Molecular Genetics Research Unit of Jacques Drouin at the
  Instituts de Recherches Cliniques de Montréal and in the Cone Laboratory 
 of Abbas Sadikot at the Montreal Neurological Institute. After returning t
 o the Netherlands for his training in Neurosurgery at the Academic Medical
  Center in Amsterdam\, he continued studying the aphakia mouse model in bo
 th the Cone Laboratory and the department of Anatomy and Neurosciences of 
 Henk Groenewegen and Pieter Voorn at the Free University of Amsterdam. He 
 obtained his PhD at the University of Amsterdam in 2011. During neurosurgi
 cal training\, he was trained in deep brain stimulation (DBS) by Andries B
 osch and Rick Schuurman. His research interests focus on improving the out
 come of DBS surgery in established indications (such as Parkinson's diseas
 e and essential tremor) and the application of experimental DBS in new ind
 ications. Since 2009\, he acted as a co-investigator on clinical trials st
 udying subthalamic nucleus versus globus pallidus DBS in Parkinson's disea
 se\, nucleus accumbens DBS in obsessive-compulsive disorder\, internal cap
 sule DBS in depression and anorexia nervosa\, and general anesthesia versu
 s local anesthesia in DBS for Parkinson's disease. He initiated several re
 search projects to improve the radiological and neurophysiological targeti
 ng of DBS surgery. Since 2017\, he acts as principal investigator of a cli
 nical trial studying the effects of DBS of the central thalamus in patient
 s with disorders of consciousness\, for which he created a multidisciplina
 ry national research alliance.\n\n\nSupported by the generosity of the Kil
 lam Trusts \, The Neuro’s Killam Seminar series hosts outstanding guest sp
 eakers.\n
DTSTART:20220426T200000Z
DTEND:20220426T210000Z
SUMMARY:Killam Seminar Series: Deep brain stimulation: new targets\, new te
 chniques\, new indications
URL:/neuro/channels/event/killam-seminar-series-deep-b
 rain-stimulation-new-targets-new-techniques-new-indications-338863
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