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UID:20250909T071903EDT-0070ejCfdM@132.216.98.100
DTSTAMP:20250909T111903Z
DESCRIPTION:\n	Many key biological processes like receptor recycling\, deact
 ivation and degradation\, antigen presentation\, autophagy\, and the elimi
 nation of microbial pathogens\, to mention a few\, involve dynamic\, often
  extreme restructuring of the intracellular membranes. These complex tasks
  are performed by a molecular sorting machinery in combination with coat p
 roteins and force-generating motors that drive membrane deformation and ex
 tension. As a result\, selected components are delivered to vesicles and t
 ubules that are vectorially directed to intracellular destinations encoded
  by determinants exposed on their cytosolic surface.\n\nSo often\, we tend
  to ignore how these dynamic events are tightly coordinated by the luminal
  contents (i.e. fluid) of membrane-bound organelles. In immune cells that 
 turnover the equivalent of their entire surface membrane and engulf the vo
 lumetric equivalent of their cytosol in a matter of hours\, fluid traffic 
 cannot be ignored – in fact\, it can be readily studied. I will discuss ou
 r recent findings that describe how the transport of ions and organic solu
 tes in endosomes and lysosomes control membrane traffic. The molecular mec
 hanisms are scaled to the tissue level to understand the importance of flu
 id traffic in the immune response to cellular damage.\n\nThis seminar will
  be offered both in-person and online. Details in attached poster. Masks a
 nd 1m distancing required.\n\n \n
DTSTART:20211112T160000Z
DTEND:20211112T170000Z
LOCATION:Room 1034\, McIntyre Medical Building\, CA\, QC\, Montreal\, H3G 1
 Y6\, 3655 promenade Sir William Osler
SUMMARY:In-person seminar - Fluid endocytosis and traffic in cells and its 
 role in immune surveillance
URL:/physiology/channels/event/person-seminar-fluid-en
 docytosis-and-traffic-cells-and-its-role-immune-surveillance-332114
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